Despite its wonder drug label, Prozac is not the first successful antidepressant. Many psychiatrists, patients, and families have remarked upon Prozac’s ability to enhance the patient’s outlook, energy level, and mood, but the truth is that many other medications work just as well as Prozac in countering the effects of depression. For instance, in clinical scientific studies. Prozac and other antidepressants have a similar rate of success and a similar onset of action (one to two weeks for most people, although in many cases up to six weeks may need to pass before symptoms are relieved). Although carefully controlled studies of more than one or two years have not been completed, early reports suggest that Prozac, the other SSRIs, and Effexor are as effective is preventing depressive relapses in recurrent or unipolar depression as are the classic tricyclic antidepressants used over the last thirty years, such as amitriptyline (Elavil), imipramine (Tofranil), desipramine (Norpramine) and nortriptyline (Pamelor). It is also my impression that, when combined with lithium, Prozac appears to be effective in preventing relapses in patients with unipolar recurrent depression or bipolar manic depression.
addition, most patients receiving Prozac have to take only one capsule a day compared to previous antidepressants that require between three and six a day.
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